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Publications

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Hooper Lab publications:

75. Pendse, M. and Hooper, L.V. (2016) Mum's microbes boost baby's immunity. Nature 533, 42-43. Article preview
74. Hu, S., Peng, L., Kwak, Y.-T., Tekippe, E.M., Pasare, C., Malter, J.S., Hooper, L.V., Zaki, M.H. (2015) The DNA sensor AIM2 maintains intestinal homeostasis via regulation of epithelial antimicrobial host defense. Cell Reports 13, 1-15. Abstract and full text
73. Lopez-Medina, E., Fan, D., Coughlin, L.A., Ho, E.X., Lamont, I.L., Reimmann, C., Hooper, L.V., Koh, A.Y. (2015) Candida albicans inhibits Pseudomonas aeruginosa virulence through suppression of pyochelin and pyoverdine biosynthesis. PLoS Path. 11, e1005129. Abstract and full text
72. Fan, D., Coughlin, L.A., Neubauer, M.M., Hooper, L.V., Koh, A.Y. (2015) Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization. Nat. Med. 21, 808-814. Article preview
71. Sturge, C.R., Burger, E., Raetz, M., Hooper, L.V., Yarovinsky, F. (2015) Developmental regulation of IFN-gamma production by mouse neutrophil precursor cells. J. Immunol., 195, 36-40. Article preview
70. Hooper, L.V. (2015) Epithelial cell contributions to intestinal immunity. Adv. Immunol. 126, 129-172. Abstract
69. Bel, S. and Hooper, L.V. (2015) A bacterial nudge to T-cell function. Nature, 526:328-330. Article preview
68. Propheter, D. C. and Hooper, L.V., (2015) Bacteria come into focus: New tools for visualizing the microbiota. Cell Host and Microbe, 18:392-394. Abstract and full text
67. Kleiner, M., Hooper, L.V., Duerkop, B.A. (2015) Evaluation of methods to purify virus-like particles for metagenomics sequencing of intestinal viromes. BMC Genomics. Abstract and full text
66. Mukherjee, S. and Hooper, L.V. (2015) Antimicrobial defense of the intestine. Immunity, 42, 28-39. Abstract and full text
65. Hooper, L.V. (2014) Innate lymphoid cells sweeten the pot. Science 345, 1248-1249. [PMID: 25214594]
64. Yu, X., Wang, Y., Deng, M., Li, Y., Ruhn, K.A., Zhang, C.C., Hooper, L.V. (2014) The basic leucine zipper transcription factor NFIL3 directs the development of a common innate lymphoid cell precursor. eLife 3, e04406. Abstract and full text
63. Mirpuri J, Raetz M, Sturge CR, Wilhelm CL, Benson A, Savani RC, Hooper LV, Yarovinsky F. (2014) Proteobacteria-specific IgA regulates maturation of the intestinal microbiota. Gut Microbes. 5(1):28-39. Abstract and full text
62. Derebe MG1, Zlatkov CM, Gattu S, Ruhn KA, Vaishnava S, Diehl GE, MacMillan JB, Williams NS, Hooper LV. (2014) Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection. Elife. 3:e03206. Abstact and full text

This paper was featured in the following forums: Trends in Immunology ("Serum amyloid A proteins take retinol for a ride") http://www.cell.com/trends/immunology/fulltext/S1471-4906(14)00173-2 eLife ("An ambulance for retinol") http://elifesciences.org/content/3/e04246 Faculty of 1000 http://f1000.com/prime/718512171?subscriptioncode=f1ffcc2d-e303-4298-8c03-4b5cf37d6206
61. Mukherjee, S., Zheng, H., Derebe, M., Callenberg, K., Partch, C.L., Rollins, D., Propheter, D.C., Rizo, J., Grabe, M., Jiang, Q.-X., and Hooper, L.V. (2014) Antibacterial membrane attack by a pore-forming intestinal C-type lectin. Nature 505, 103-107 Abstract and full text
60. Yu, X., Rollins, D., Ruhn, K.A., Stubblefield, J.J., Green, C.B., Kashiwada, M., Rothman, P.B., Takahashi, J.S., and Hooper, L.V. (2013) Th17 cell differentiation is regulated by the circadian clock. Science 42, 727-730. Abstract and full text
59. Duerkop, B.A., and Hooper, L.V. (2013) Resident viruses and their interactions with the immune system. Nature Immunology 14, 654-659. Abstract and full text
58. Benjamin, J.L., Sumpter, R., Levine, B., and Hooper, L.V. (2013) Intestinal epithelial autophagy is essential for host defense against invasive bacteria. Cell Host & Microbe 13, 723-724. Abstract and full text
57. Guarner, F., Hooper, L.V., and Nunez, G. (2013) Understanding the microbiota in the midst of Renaissance architecture and olive groves (Meeting Report). Immunology 14, 101-105. Abstrack and full text
56. Raetz, M., Hwang, S.-H., Wilhelm, C., Kirkland, D., Benson, A., Sturge, C., Mirpuri, J., Vaishnava, S., Hou, B., DeFranco, A.L., Gilpin, C.J., Hooper, L.V., and Yarovinsky, F. (2013) Parasite-induced TH1 cells and intestinal dysbiosis cooperate in IFN-gamma-dependent elimination of Paneth cells. Nature Immunology 14, 136-142. Abstract and full text
55. Duerkop, B.A., Clements, C.V., Rollins, D., Rodrigues, J.L.M, and Hooper, L.V. (2012) A composite bacteriophage alters colonization by an intestinal commensal bacterium. Proceedings of the National Academy of Sciences USA, 109, 17621-17626. Abstract and full text
54. Du, Y., Yang, M., Lee, S., Behrendt, C.L., Hooper, L.V., Saghatelian, A., Wan, Y. (2012) Maternal western diet causes inflammatory milk and TLR2/4-dependent neonatal toxicity. Genes & Development 26, 1306-1311. Abstract and full text
53. Gallo, R.L., Hooper, L.V. (2012) Epithelial antimicrobial defence of the skin and intestine. Nature Reviews Immunology 12, 503-516. Abstract and full text
52. Hooper, L.V., Littman, D.R., Macpherson, A.J. (2012) Interactions between the microbiota and the immune system. Science 336, 1268-1273. Abstract and full text
51. Vaishnava, S., Yamamoto, M., Severson, K.M., Ruhn, K.A., Yu, X., Koren, O., Ley, R., Wakeland, E.K., and Hooper, L.V. (2011) The antibacterial lectin RegIIIγ promotes the spatial segregation of microbiota and host in the intestine. Science, 334, 255-258. Abstract and full text
50. Hooper, L.V. (2011) You AhR what you eat: linking diet and immunity. Cell. 147, 489-491. Abstract and full text
49. Kuss, S.K., Etheredge, C.A., Best, G.T., Frierson, J.M., Pruijssers, A.J., Hooper, L.V., Dermody, T.S., Pfeiffer, J.K. Intestinal microbiota promote enteric virus replication and systemic pathogenesis. Science.249-252. Abstract and full text
48. Li, X.-D., Chiu, Y.-H., Ismail, A.S., Behrendt, C.L., Wight-Carter, M., Hooper, L.V., Chen, Z.J. The RIG-I-MAVS pathway detects commensal bacterial RNA and induces an immune response that prevents experimental colitis. Proceedings of the National Academy of Sciences USA.17390-17395 Abstract and full text
47. Ismail, A.S., Severson, K.M., Vaishnava, S., Behrendt, C.L., Yu, X., Benjamin, J.L., Ruhn, K. Hou, B., DeFranco, A.L., Yarovinsky, F., and Hooper, L.V. (2011) γσ intraepithelial lymphocytes are essential mediators of host-microbial homeostasis at the intestinal mucosal surface. Proceedings of the National Academy of Sciences USA, 108, 8743-8748. Abstract and full text
46. Vaishnava, S., and Hooper, L.V. (2011) Eat your carrots! T cells are RARing to go. Immunity 34, 290-292. Abstract and full text
45. Lehotzky, R.E.*, Partch, C.L.*, Mukherjee, S., Cash, H.L., Goldman, W.E., Gardner, K.H., and Hooper, L.V. (2010) Molecular basis for peptidoglycan recognition by a bactericidal lectin. Proceedings of the National Academy of Sciences USA 107, 7722-7727. *Equal contributions Abstract and full text
44. Hooper, L.V. and Macpherson, A.J. (2010) Immune adaptations that maintain homeostasis with the intestinal microbiota. Nature Reviews Immunology 10, 159-169. Abstract and full text
43. Lai, Y., Di Nardo, A., Nakatsuji, T., Leichtle, A., Yang, Y., Cogen, A. L., Wu, Z.-R., Hooper, L. V., Schmidt, R. R., von Aulock, S., Radek, K. A., Huang, C.-M., Ryan, A. F., and Gallo, R. L. (2009) Commensal bacteria regulate Toll-like receptor 3�dependent inflammation after skin injury. Nature Medicine 15, 1377-1382. Abstract and full text
42. Duerkop, B., Vaishnava, S., and Hooper, L.V. (2009) Immune responses to the microbiota at the intestinal mucosal surface. Immunity 31, 368-376. Abstract and full text
41. Benson, A., Pifer, R., Behrendt, C.L., Hooper, L.V., and Yarovinsky, F. (2009) Gut commensal bacteria direct a protective immune response against the pathogen Toxoplasma gondii. Cell Host & Microbe 6, 187-196. Abstract and full text
40. Hooper, L. V. (2009) Do symbiotic bacteria subvert host immunity? Nature Reviews Microbiology 7, 367-374. Abstract and full text
39. Ismail, A. S., Behrendt, C. L., and Hooper, L. V. (2009) Reciprocal interactions between commensal bacteria and γσ intraepithelial lymphocytes during mucosal injury. Journal of Immunology 182, 3047-3054. Abstract and full text
38. Mukherjee, S.*, Partch, C.L.*, Lehotzky, R.E., Whitham, C.V., Chu, H., Bevins, C.L., Gardner, K.H., and Hooper, L.V. (2009) Regulation of C-type lectin antimicrobial activity by a flexible N-terminal prosegment. Journal of Biological Chemistry 284, 4881-4888. *Equal contributions Abstract and full text
37. Vaishnava, S., Behrendt, C. L., Ismail, A.S., Eckmann, L., and Hooper, L. V. (2008) Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proceedings of the National Academy of Sciences USA 105, 20858-20863. Abstract and full text
36. Mukherjee, S., Vaishnava, S., and Hooper, L.V. (2008) Multi-layered regulation of intestinal antimicrobial defense. Cellular and Molecular Life Sciences 65, 3019-3027. Abstract and full text
35. Vaishnava, S., and Hooper, L. V. (2007) Alkaline phosphatase: keeping the peace at the gut epithelial surface. Cell Host & Microbe 2, 365-367. Abstract and full text
34. Hooper, L. V. (2006) Nature Journal Club. Nature 442, 851.
33. Cash, H. L., Whitham, C. V., Behrendt, C. L., and Hooper, L. V. (2006) Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science 313, 1126-1130. Abstract and full text
32. Cash, H. L., Whitham, C. V., and Hooper, L. V. (2006) Refolding, purification, and characterization of human and murine RegIII proteins expressed in Escherichia coli. Protein Expression and Purification 48, 151-159. Abstract and full text
31. Ismail, A. and Hooper, L. V. (2005) Bacterial contributions to intestinal epithelial barrier integrity. American Journal of Physiology: Gastrointestinal and Liver Physiology 289, G779-G784. Abstract and full text
30. Cash, H. L. and Hooper, L. V. (2005) How commensal bacteria shape intestinal immune system development. ASM News 71, 77-83.
29. Hooper, L.V. (2005) Resident bacteria as inductive signals in mammalian gut development. In The Influence of Cooperative Bacteria on Animal Host Biology, (M. J. McFall-Ngai, B. Henderson, and E.G. Ruby, editors), Cambridge University Press, London, pp. 449-264.
28. Hooper, L. V. (2004) Laser microdissection: Exploring host-bacterial interactions at the front lines. Current Opinion in Microbiology 7, 290-295. Abstract and full text
27. Hooper, L. V. (2004) Bacterial contributions to mammalian gut development. Trends in Microbiology 12, 129-134. Abstract and full text

Publications from LVH postdoctoral work, Washington University (1996-2003)

26. Backhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, C. F., and Gordon, J. I. (2004) The gut microbiota as an environmental factor that regulates fat storage. Proceedings of the National Academy of Sciences USA 101, 15712-15723. Abstract and full text
25. Gordon, J. I., Stappenbeck, T. S., and Hooper, L. V. (2003) Response from Jeffrey I. Gordon et al.: Commensal bacteria make a difference. Trends in Microbiology 11, 150-151. Abstract and full text
24. Xu, J., Bjursell, M. K., Himrod, J., Deng, S., Carmichael, L. K., Chiang, H. C., Hooper, L. V., and Gordon, J. I. (2003) A genomic view of our symbiosis with Bacteroides thetaiotaomicron. Science 299, 2074-2076. Abstract and full text
23. Hooper, L. V., Stappenbeck, T. S., Hong, C. V., and Gordon, J. I. (2003) Angiogenins: a new class of microbicidal proteins involved in innate immunity. Nature Immunology 4, 269-273. Abstract and full text
22. Stappenbeck T. S., Hooper, L. V., Manchester, J. K., Wong, M. H., Gordon, J. I. (2002) Laser capture microdissection of the mouse intestine: characterizing mRNA and protein expression, and profiling intermediary metabolism in specified cell populations. Methods in Enzymology 356, 167-196. Full text
21. Hooper, L. V., Mills, J. C., Roth, K.A., Stappenbeck, T.S., Wong, M. H., and Gordon, J. I. (2002) Combining gnotobiotic mouse models with functional genomics to define the impact of the microflora on host physiology. In Methods in Microbiology: Molecular Cellular Microbiology (P. J. Sansonetti, A. Zychlinsky, editors), Academic Press, London, pp. 559-589.
20. Dunne, W. M., Pinckard, J. K., and Hooper, L. V. (2002) Guest Commentary: Clinical microbiology in the year 2025. Journal of Clinical Microbiology 40, 3889-3893. Abstract and full text
19. Hooper, L.V., Midtvedt, T., and Gordon, J. I. (2002) How host-microbial interactions shape the nutrient environment of the mammalian intestine. Annual Review of Nutrition 22, 283-307. Abstract and ful text
18. Stappenbeck, T. S., Hooper, L. V., and Gordon, J. I. (2002) Developmental regulation of intestinal angiogenesis by indigenous microbes via Paneth cells. Proceedings of the National Academy of Sciences USA 99, 15451-15455. Abstract and full text
17. Hooper, L. V., and Gordon, J. I. (2001) Commensal host-bacterial relationships in the gut. Science 292, 1115-1118. Abstract and full text
16. Hooper, L. V., and Gordon, J. I. (2001) Glycans as legislators of host-microbial interactions: spanning the spectrum from symbiosis to pathogenicity. Glycobiology 11, 1R-10R. Abstract and full text
15. Hooper, L.V., Wong, M., Thelin, A., Falk, P., Hansson, L., and Gordon, J.I. (2001) Molecular analysis of commensal host-microbial relationships in the intestine. Science 291, 881-884. Abstract and full text
14. Lopez-Boado, Y.S., Wilson, C.L., Hooper, L.V., Gordon, J.I., Hultgren, S.J., Parks, W.C. (2000) Bacterial exposure induces and activates matrilysin in mucosal epithelial cells. Journal of Cell Biology 148, 1305-15. Abstract and full text
13. Hooper, L.V., Xu, J., Falk, P.G., Midtvedt, T., and Gordon, J.I. (1999) A molecular sensor that allows a gut commensal to control its nutrient foundation in a competitive ecosystem. Proceedings of the National Academy of Sciences USA 96, 9833-9838. Abstract and full text
12. Hooper, L.V., Falk, P.G., and Gordon, J.I. (2000) Analyzing the molecular foundations of commensalism in the mouse intestine. Current Opinion in Microbiology 3, 79-85. Abstract and full text
11. Falk, P.G., Hooper, L.V., Midtvedt, T., and Gordon, J.I. (1998) Creating and maintaining the gastrointestinal ecosystem: what we know and need to know from gnotobiology. Microbiology and Molecular Biology Reviews 62, 1157-1170. Abstract and full text
10. Hooper, L.V., Bry, L., Falk, P.G., and Gordon, J.I. (1998) Host-microbial symbiosis in the mammalian intestine: exploring an internal ecosystem. Bioessays 20, 336-343. Abstract and full text

Publications from LVH graduate work, Washington University (1989-1996)

9. Hooper, L.V., Manzella, S.M., and Baenziger, J.U. (1997) The biology of sulfated oligosaccharides. In Glycosciences: Status and perspectives (H.-J. Gabius and S. Gabius, editors), Chapman and Hall, Gmbh, Weinhein, Deutchland, pp. 261-272.
8. Gordon, J.I., Hooper, L.V., McNevin, S.M., Wong, M., and Bry, L. (1997) Epithelial cell growth and differentiation. III. Promoting diversity in the small intestine: conversations between the microflora, the epithelium, and diffuse GALT. American Journal of Physiology 273, G565-570.
7. Hooper, L.V., Manzella, S.M., and Baenziger, J.U. (1996) From legumes to lymphocytes: biological functions for sulfated carbohydrates. FASEB Journal 10, 1137-1146. Abstract and full text
6. Manzella, S.M., Hooper, L.V., and Baenziger, J.U. (1996) Oligosaccharides containing β1,4-linked N-acetylgalactosamine, a paradigm for protein-specific glycosylation. Journal of Biological Chemistry 271, 12117-12120. Abstract and full text
5. Hooper, L.V., Hindsgaul, O., and Baenziger, J.U. (1995) Purification and characterization of the GalNAc-4-sulfotransferase responsible for sulfation of GalNAcβ,4GlcNAc-bearing oligosaccharides. Journal of Biological Chemistry 270, 16327-16332. Abstract and full text
4. Hooper, L.V., Beranek, M.C., Manzella, S.M., and Baenziger, J.U. (1995) Differential expression of GalNAc-4-sulfotransferase and GalNAc-transferase results in distinct glycoforms of carbonic anhydrase VI in parotid and submaxillary glands. Journal of Biological Chemistry 270, 5985-5993. Abstract and full text
3. Hooper, L.V. and Baenziger, J.U. (1993) Sulfotransferase and glycosyltransferase analyses using a 96-well filtration plate. Analytical Biochemistry 212, 128-133. Abstract and full text
2. Skelton, T.P., Hooper, L.V., Srivastava, V., Hindsgaul, O., and Baenziger, J.U. (1991) Characterization of a sulfotransferase responsible for the 4-O-sulfation of terminal β-N-acetyl-D-galactosamine on asparagine-linked oligosaccharides of glycoprotein hormones. Journal of Biological Chemistry 266, 17142-17150. Abstract and full text
1. Brown, E., Hooper, L., Ho, T., and Gresham, H. (1990) Integrin-associated protein: A 50-kD plasma membrane antigen physically and functionally associated with integrins. Journal of Cell Biology 111, 2785-2794. Abstract and full text